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| Spinal Cord Injury - The Solutions of the Future | |
| Till the early part of the last century, cases of Spinal Cord Injuries
invariably ended fatally within a few weeks of the injury, if not at the
time of trauma itself. A radical change in the approach to a patient with
SCI occurred soon after the Second World War. The surgical techniques were
developed during the 1950s and 60s. The last two decades brought in
significant advancements in Spinal Injury Management including
methlyprednisolone and GM1 therapy, intracthecal baclofen pump, titanium
cage for vertebral repair, delayed decompression for restoring function,
ileal conduits, stents and artificial sphincters for bladder and bowel,
sacral anterior root stimulator, tendon transfers to restore hand grasp
strength, etc. It also brought in promising therapies like IN-1 antibody
stimulating regeneration drugs like 4 AP improving in people with chronic
spinal injury and neurotrophin-secreting fibroblast transplants. Today, a
spinal surgeon has a significant armamentarium with which to tackle the
problem of SCI. The future of SCI Management lies in-
The current clinical trials are in the field of fetal cell transplants, 4AP,
activated macrophage transplants, porcine neural stem cell transplants,
alternation current electrical stimulation, AIT-082, Peripheral nerve bridge,
fetal stem cell and fetal stem cell olfactory ensheathing glial transplants. |
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